Ten problems I care most by Michel Deza, Ecole Normale Superieure, Paris The following 10 problems of Applied Geometry will be presented: I. Perfect matroid designs II. a) Infinite hypermetrics b) $l_1$-embedding of complexes III.a) Fullerenes: $IQ$, Skyrmions, viruses b) Space fullerenes IV. a) Zigzags and railroads in fullerenes b) Zigzags and Lins triality of maps V. a) Three classes of exotic plane graphs b) Ambiguous boundaries of polycycles VI. Extreme physical distances Not all of above problems mine and not all are purely mathematical. But they represent my main areas of interest in recent years.