Adrian Altenhoff
I am working as Project Manager for the OMA Browser. The OMA project is a SIB funded core resource that provides orthology predictions among thousands of complete genomes. The project is lead jointly by Prof. Christophe Dessimoz and Prof. Gaston Gonnet.
I did my first degree in Computer Science at ETH Zurich (2000-2005). From 2006 to 2012 I did my PhD under the supervision of Gaston Gonnet.
ContactETH Zurich |
Research Fields
- Identification of orthologs and paralogs
- Phylogenetic tree reconstruction
- Computational molecular evolution
Selected Publications
see also my Google Scholar profile for a complete list
Adrian Altenhoff, Nives Škunca, Natasha Glover, Clément-Marie Train, Anna Sueki, Ivana Piližota, Kevin Gori, Bartlomiej Tomiczek, Steven Müller, Henning Redestig, Gaston H. Gonnet, and Christophe Dessimoz (2015) The OMA orthology database in 2015: function predictions, better plant support, synteny view and other improvements. Nucleic Acids Research, 43 (D1): D240-D249 NAR
Lucas D. Wittwer, Ivana Piližota, Adrian M. Altenhoff and Christophe Dessimoz (2014) Speeding up all-against-all protein comparisons while maintaining sensitivity by considering subsequence-level homology. PeerJ, 2:e607 PeerJ
Daniel A. Dalquen, Adrian M. Altenhoff, Gaston H. Gonnet, Christophe Dessimoz (2013) The impact of gene duplication, insertion, deletion, lateral gene transfer and sequencing error on orthology inference: a simulation study. PLoS One, 8(2): e56925 PLoS
Adrian M. Altenhoff, Manuel Gil, Gaston H. Gonnet, Christophe Dessimoz (2013) Inferring Hierarchical Orthologous Groups From Orthologous Gene Pairs PLoS One, 8(1): e53786 PLoS
Adrian M. Altenhoff, Romain Studer, Marc Robinson-Rechavi and Christophe Dessimoz (2012): Resolving the ortholog conjecture: orthologs tend to be weakly, but significantly, more similar in function than paralogs PLoS Computational Biology, 8(5): e1002514 PLoS
Nives Škunca, Adrian M. Altenhoff and Christophe Dessimoz (2012): Quality of Computationally Inferred Gene Ontology Annotations PLoS Computational Biology, e1002533 PLoS
Adrian M. Altenhoff and Christophe Dessimoz (2012): Inferring Orthology and Paralogy Evolutionary Genomics: Statistical and Computational methods (M Anisimova, Editor), Methods in Molecular Biology, Springer Humana, Vol. 855. [Springer]
Adrian M. Altenhoff, Adrian Schneider, Gaston Gonnet and Christophe Dessimoz (2011): OMA 2011: Orthology Inference Among 1,000 Complete Genomes Nucleic Acids Research 39 (suppl 1): D289-D294 NAR
Marc Wüest, Christoph Frei, Adrian Altenhoff, Martin Hagen, Michael Litschi and Christoph Schär (2010): A gridded hourly precipitation dataset for Switzerland using rain-gauge analysis and radar-based disaggregation Int. J. Climatol. 30(12): 1764-1775 JOC
Adrian M. Altenhoff and Christophe Dessimoz (2009): Phylogenetic and Functional Assessment of Orthologs Inference Projects and Methods PLoS Computational Biology,5(1): e1000262 PLoS
Adrian M. Altenhoff, Olivia Martius, Mischa Croci-Maspoli, Cornelia Schwierz and Huw C. Davies (2008): Linkage of Atmospheric Blocks and Synoptic-scale Rossby Waves Tellus, 60A: 1053-1063 Tellus
Adrian M. Altenhoff, Jens H. Walther and Petros Koumoutsakos (2007) A stochastic boundary forcing for dissipative particle dynamics J Comput Phys, 225(1): 1125-1136 Elsevier
Teaching Assistant
- Computational Biology, Prof Gaston Gonnet
- Modelling and Simulation (Principal Assistant), Prof. Gaston Gonnet
- Computer Science I for Civil, Environmental and Geomatic EngineeringStudents, Prof Rico Jackob
- Anwendungsnahes Programmieren and Einsatz von Informatikmitteln, both Prof. H Hinterberger
- Computer Science II, Prof. Friedemann Mattern
- Symbolic & Numerical Computing, Prof. Petros Koumoutsakos
Forum for Women in Computer Science
From September 2007 to September 2011 I was co-heading the Forum for Women in Computer Science (Frauenförderung). Its primary goal is to increase the number of female CS-students.